5/23/2018

ANALYSIS CELL BIOLOGY FOR CSIR NET LIFE SCIENCE EXAM




BROAD ANALYSIS OF CELL BIOLOGY IN CSIR-NET EXAM

Dr. MOHIT GUPTA
(For Grassroots Academy, Delhi)

ANALYSIS OF THE TRENDS OF CSIR-NET QUESTION PAPER....



 BROAD ANALYSIS OF CELL BIOLOGY IN CSIR-NET EXAM

Exam Year
             Part - B
             Part - C
Dec 2016
3
6
June 2016
6
5
Dec 2015
3
6
June 2015
5
5
Dec 2014
2
7
June 2014
3
6
Dec 2013
6
7
June 2013
3
6
Dec 2012
3
7
June 2012
6
4


Cell Biology (CB) is one of the widest subjects in the syllabus and regularly large numbers of questions are being asked and are quite useful in cracking the exam. The problem with this subject is that no single book can be recommended, and different author’s present different perspectives……..another issue is that animal cell biology differs slightly from plant cell biology e.g. Most plants are immune to cyanide poisoning where as animals are prone to cyanide……many a times clinical perspectives are asked…for which we have medical cell biology books …….so it becomes difficult for a student to get the entire perspective…..

As we can analyze in the table above that consistently 6-7 questions are being asked from cell biology in Part-C and one has to only attempt 25 questions in Part-C  i.e. approx 30%. In Part-B there seems to be inconsistent pattern, from minimum of 2 to maximum 6 questions…….nevertheless CB can contribute immensely to your success.

CB questions in Part-B are pretty direct…….but to solve Part-C one needs deeper and thorough analysis as questions are experimental in nature….and one needs to study standard authors..e.g  Alberts……./ Lodish……../ Karp……../ Pollard…./ Cooper…./ Wayne....../ Cell by Lewin…/…..No Indian authors are recommended..



Experimental nature of some questions in Part-C

Q.  A pharmacy student designed a drug to specifically target the receptors for retinoic acid in order to prevent stem cell differentiation. After in vitro trial, the investigaton found that the cells underwent differentiation and the drug seemed to be ineffective. The following reasons were given by the student
A.  The size of the drug exceeded the size of molecules that could cross the membrane
B.  The drug small in size but hydrophobic in nature
C.  The drug did not bind to its receptors
Which of the above could be the probable reason for drug ineffectiveness?
1. Only C                              2.  A and C                           3. A, B and C                                       4. Only B

Q. You have isolated a short chain polypeptide from a bacteria which upon administering to animal cells in culture is demonstrated to get transport to mitochondria and to cause mitochondrial membrane disruption. This peptide is being considered for its therapeutic effects on cancer and is to be tested for its anticancer properties in the following models of the disease.
A. cancer with Apaf-1 mutation
B. cancer where Bax genes are inactivated.
C. cancer where Bak genes are inactivated.
1. Only A
2. B and C
3. A and B
4. A and C




In analysis below…..we have not considered Mitochondria /Respiration & Chloroplast/Photosynthesis as they are part of Plant Physiology in CSIR-NET syllabus.
Inferences drawn from past papers are......
1. Questions from Membrane and membrane transport are consistently being asked…..2-3 questions every exam….so be thorough……..especially lipid composition n types in membranes…………role of temperature and composition in influencing membrane fluidity…….importance of membrane asymmetry…..Lipid Raft…....Liposomes etc….and certain techniques like Freeze fractured ……..hydropathycurve…….FRAP etc.

2. Another area of utmost importance is Molecular basis of Cell cycle and Cancer……..these are related topics because any defect in cell cycle regulation can result in cancer development…….3 - 4 questions have been asked every time..so have deeper analysis of these topics……and analyze past year net papers to get the feel of questions.

3. Signal Transduction i.e. Cell Signaling is a very wide topic………..with differences in animals, plants and bacterial signaling mechanisms………this topic assumes importance as we can get direct questions from here and indirectly this area helps in solving questions from cancer biology.

4. Questions from Endomembrane system ( ER, Golgi, Lysosomes, Endosomes, Vesicular transp, Exo & Endocytosis) are also consistant………out of 9 questions asked 6 are from Part-C.

5. Cellular Communication i.e. cell-cell interaction and ECM…..is equally important especially for Part-B…..every exam question has popped up from here….though simple in nature.

6. The analysis shows an important facet i.e. very few asked from Cytoskeleton…….even though this topic is one of the widest in cell biology…….and it takes multiple lectures to cover it……but indirect questions on microtubules have been asked in relation to cell cycle…ie spindle fibres……but one cannot take a chance.


Hope the above analysis helps you in planning your strategy for the coming exam…and remember “There is no short cut to success”


5/22/2018



BROAD ANALYSIS OF PLANT PHYSIOLOGY IN CSIR-NET EXAM

Dr. MOHIT GUPTA
(For Grassroots Academy, Delhi)

ANALYSIS OF THE TRENDS OF CSIR-NET QUESTION PAPER....




                                   
Hello Friends,

Its only few days left for CSIR-NET Exam and you all must be busy with final revisions and organization of the entire syllabus…..We at Grassroots thought it prudent to provide you with brief analysis of the entire Plant Physiology section and the recent trend of topics being asked…….
If we analyze the table below, we could clearly make out……that at least 10 – 12 questions are consistently being asked from plant physiology i.e. 6 – 7 questions in Part-C (nearly 30% of total to be attempted in Part-C) and 4 – 5 questions in Part-B………which could immensely contribute to ones success, at least students from pure sciences like M.Sc. Botany.

CLICK HERE FOR FULL ARTICLE


12/23/2017



JNU Biotechnology Entrance Examination


(Analysis of General Chemistry Portion)




Jawaharlal Nehru University, New Delhi conducts combined entrance examination for the admission in M.Sc. Biotechnology (CEEB) every year, on behalf of nearly 33 universities and it alone offers approx. 500 + seats.

The paper is divided into two parts; Part - A & Part - B
Chemistry is the compulsory portion of both parts, there are usually 15 questions from chemistry out of 60 questions in the Part - A while the number of questions being asked in Part - B from chemistry portion are usually 16 to 18. 

For the ease of study we may divide chemistry portion into four categories viz General chemistry, Inorganic chemistry, Organic chemistry and Physical chemistry. Here in this post we will discuss the trends and number of questions being asked from the General chemistry.

General chemistry includes the following chapters: Laws of chemistry, Mole concept, Atomic structure, Radioactivity, Chemical bonding, Redox chemistry. Let’s first have a look at the number of questions being asked from this portion during the last five years.
  
              
        Part
    
       Year

Part - A

Part - B

Total
2014
5 (out of 15)
4 (out of 16)
9
2013
4 (out of 15)
3 (out of 17)
7
2012
4 (out of 15)
2 (out of 18)
6
2011
5 (out of 15)
3 (out of 18)
8
2010
4 (out of 15)
3 (out of 18)
7
















It is noteworthy to mention over here that no question was asked from the chapter Laws of chemistry.
If we further analyze the papers we observe that maximum questions were asked from the chapter chemical bonding and atomic structure.


   
   Topic

  Year

Mole concept

Atomic structure

Radioactivity

Chemical Bonding

Redox Chemistry
2014
0
4
0
3
2
2013
1
1
1
3
1
2012
0
3
1
2
0
2011
1
2
2
3
0
2010
0
2
1
3
1





Another important perspective we draw....... is that two of the above mentioned topics i.e. atomic structure and radioactivity also offer a few questions in Physics portion of both Part A & B. 
Here i present a brief analysis of the trends in physics portion (both Part A & Part B) of last five year papers.

              
       Topic
       Year

Atomic Structure

Radioactivity
2014
2
2
2013
0
0
2012
2
2
2011
4
2
2010
1
1















After analyzing the past trend i firmly suggest that if one is well versed with above five topics (mole concept, atomic structure, radioactivity, chemical bonding and redox chemistry) it’s a good stake, you surely will find not less than ten questions in both Chemistry and Physics portions.

Enquiries and suggestion are welcome.
Thank you all
Good luck.